All Adobe users should update immediately because exploits for the vulnerability have been reported by many industry sources. Symantec also published a well-done analysis here.
Chrome's silent update feature and now the included PDF viewer make it a viable option for light PDF usage.
-- As the CTO for Qualys, Wolfgang Kandek is responsible for product direction and all operational aspects of the QualysGuard platform and its infrastructure. Wolfgang has more than 20 years of experience in developing and managing information systems. His focus has been on Unix-based server architectures and application delivery through the Internet. Wolfgang provides the latest commentary on his blog: laws.qualys.com and also publishes his Patch Tuesday commentary to the QualysGuard channel: www.youtube.com/QualysGuard. He is a frequent source in business and trade media and speaks at industry conferences around the world, most recently at RSA 2010.