PRESS RELEASE

LAS VEGAS, NV. - (May 22, 2012) – Guidance Software Inc. (NASDAQ:GUID), the World Leader in Digital Investigations™, today announced EnCase® App Central, a new marketplace for digital investigation apps along with a software development kit and other support for its developer network.

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Guidance Software chief executive officer Victor Limongelli made the announcement at the Computer Enterprise Investigation Conference (CEIC), being held through May 24th in Las Vegas.

EnCase App Central will include both free and paid EnScript® modules, which are applications that customize and automate functions in Guidance Software’s EnCase digital investigation software platform. Also available in the marketplace will be reporting templates, evidence processor templates and tools that help integrate EnCase with third-party applications.

Also at CEIC, Guidance Software Chief Technology Officer Shawn McCreight announced the EnCase SDK that enables software developers to update their existing EnScript modules or to build new ones for EnCase. With the EnCase SDK, developers can take advantage of improved memory performance, greater access to evidence and powerful new features such as tagging.

Developers who become members of EnCase App Central receive an EnCase developer license, the SDK and also get access to tech support and the ability to publish their resulting EnScript applications on EnCase App Central.

“EnCase App Central gives EnCase users, for the first time, one-stop shopping for the apps they need, and also gives EnCase software partners a new tool to market and monetize their work. It is a tremendous step forward for the EnCase ecosystem,” McCreight said. “Our mission right now is to tap into the creativity of our developer network for the best and most effective apps, so that the functionality available in EnCase App Central impresses our users when it opens in the fall.”

There are more than 40,000 EnCase users worldwide who can use EnScript modules to automate and augment the functionality of their EnCase software for more effective and streamlined forensic, e-discovery and cyber security investigations. The EnScript programming language has always been a key feature of EnCase, but until EnCase App Central, developers had no easy way to market and monetize their EnScript applications.

For more information, please visit:

EnCase App Central: http://www.guidancesoftware.com/appcentral

EnCase App Central Developer Network: http://www.guidancesoftware.com/appcentraldeveloper

About Guidance Software, Inc.

Guidance Software is recognized worldwide as the industry leader in digital investigative solutions. Its EnCase® platform, with more than 40,000 licenses distributed worldwide, provides the foundation for government, corporate and law enforcement organizations to conduct thorough, network-enabled, and court-validated computer investigations of any kind, such as responding to e-discovery requests, conducting internal investigations, responding to regulatory inquiries or performing data and compliance auditing - all while maintaining the integrity of the data. The EnCase Enterprise platform is used by numerous Federal Civilian and Defense agencies, more than 65 of the Fortune 100, and thousands attend Guidance Software's renowned training programs annually. For more information about Guidance Software, visit www.guidancesoftware.com.

EnCase®, EnScript®, FastBloc®, EnCE®, EnCEP®, CaseCentral®, CaseCentral eDiscovery Cloud® Guidance Software™ and Tableau™ are registered trademarks or trademarks owned by Guidance Software in the United States and other jurisdictions and may not be used without prior written permission. All other trademarks and copyrights referenced in this press release are the property of their respective owners.